Sugar acids and derivatives
Medchemexpress LLC IFN-beta Rhesus Mac 100ug
IFN-beta Protein is an immunomodulatory cytokine of the type 1 interferon family IFN-beta Protein reduces joint inflammation by inhibiting the RANKL-c-Fos signaling pathway IFN-beta Protein regulates mitochondrial fission through STAT5 PGAM5 and Drp1 to rescue neurodegeneration IFN-beta Protein Rhesus Macaque (HEK293 Fc) is the recombinant Rhesus Macaque-derived IFN-beta protein expressed by HEK293 with C-mFc labeled tag
Cayman Chemical QuercetIn 3-O-glucuronIde 10mg
A pharmacologically active flavonol glucuronide; reduced rat immobility time in the forced swim test (0.6 mg/kg); reduced stress-induced hyperthermia in mice (1.2 mg/kg)
Medchemexpress LLC D-Glucuronic acid | 6556-12-3 | 1 ML
D-Glucuronic acid is a crucial component of various anti-inflammatory proteoglycans, playing a role in embryonic development and inhibiting cell aggregation. This compound and its derivatives are known for their liver detoxifying properties and have demonstrated anti-tumor activity.
- Promotes early embryonic development
- Inhibits cell aggregation
- Functions as a liver detoxifier
- Derivatives possess anti-tumor activity
- Activates Toll-like receptor 4 (TLR4)
Medchemexpress LLC IL-18RAP Rhesus Mac 10ug | 10ug
IL-18 is a pleiotropic proinflammatory cytokine that is involved in induction of inflammatory mediators regulation of the cytotoxic activity of NK cells and T cells and differentiation and activation of both Th1 and Th2 cells IL-18 signals through its specific cell surface receptor IL-18R which comprises two subunits IL-18R and IL-18R beta IL-18 forms a signalling complex with the IL-18 receptor (R ) and (R ) chains at the plasma membrane which induces multiple inflammatory cytokines[2] IL-18R complex recruits the IL-1R- activating kinase and TNF- associated factor 6 which phosphorylates nuclear factor k - inducing kinase with subsequent activation of NF- k [3] IL-18R betaknockdown inhibits IL-18 driven tumor cell metastasis in C57/BL6 mice[4] IL-18RAP Protein Rhesus Macaque (HEK293 His) is a recombinant protein with a His label that consists of 357 amino acids (M1-R356) and is produced by HEK293 cells
Medchemexpress LLC 4-Methylumbelliferyl sulfate potassium | 15220-11-8 | 99.3% | 294.32 | 1 G
4-Methylumbelliferyl sulfate potassium is a fluorescent substrate commonly employed in biochemical and biomedical research to detect sulfatase activity. It comprises a sulfate group linked to a fluorescent molecule, which sulfatase enzymes can cleave. The cleavage of 4-Methylumbelliferyl sulfate releases a highly fluorescent product detectable via fluorescence microscopy or spectroscopy, enabling accurate detection and quantification of these enzymes in various biological samples.
- Fluorescent substrate
- Detects sulfatase activity
- Used in biochemical and biomedical research
- Enables accurate detection and quantification of enzymes
- Detectable via fluorescence microscopy or spectroscopy
Medchemexpress LLC Glucuronic acid sodium | 7182-77-6 | 1 ML
Glucuronic acid sodium is a polysaccharide that exhibits anti-inflammatory activity.
- Assists in the healing of ulcerative colitis.
- Enhances the intestinal barrier by upregulating tight junction proteins like ZO-1 and Occludin.
- Modulates gut microbiota by increasing beneficial bacterial populations while suppressing harmful ones.
Medchemexpress LLC UDP-glucuronic acid (trisodium) | 63700-19-6 | 99.9% | 646.23 | 10 MG
UDP-glucuronic acid trisodium (Uridine-5'-diphosphoglucuronic acid trisodium salt) is a critical precursor for essential glycoconjugates across biological kingdoms, including mammalian glycosaminoglycans, plant cell wall polysaccharides, and bacterial capsule glycoglycerolipids. This product is a laboratory chemical intended for research use only by qualified scientists.
- Precursor for essential glycoconjugates in various biological organisms
- Promotes migration of liver cancer cells (Huh7, SK-Hep1, SNU449) by inducing the EMT process in vitro
- Decreases E-cadherin levels and increases vimentin levels in Huh7 and SNU449 cells in vitro
- Soluble in H2O (≥ 100 mg/mL) and DMSO (20 mg/mL with warming/ultrasonic)
- Recommended storage at -20°C, sealed, away from moisture
- In solvent, recommended storage at -80°C for 6 months or -20°C for 1 month
![Apexbio Technology LLC heparin cofactor II precursor fragment [Homo sapiens] 1mg](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000096670.png-250.jpg)
Apexbio Technology LLC heparin cofactor II precursor fragment [Homo sapiens] 1mg
Heparin cofactor II precursor fragment is a thrombin inhibitor peptide targeting human thrombin (factor IIa) It is designed to inhibit thrombin activity thereby modulating blood coagulation pathways Heparin cofactor II precursor fragment exerts its biological activity primarily through serine protease inhibition facilitated in the presence of heparin or dermatan sulfate Based on these pharmacological properties heparin cofactor II precursor fragment holds research potential in investigating thrombin inhibition mechanisms blood coagulation pathways and conditions associated with altered coagulation such as heparin cofactor II deficiency and hypercoagulability disorders
Medchemexpress LLC 4-methylumbelliferyl α-L-iduronide | 66966-09-4 | MFCD00135894 | 99.0% | 352.29 g/mol | C16H16O9 | 1 MG
4-Methylumbelliferyl α-L-iduronide is a fluorogenic biochemical reagent used as a substrate to measure α-L-iduronidase activity. Enzymatic cleavage releases 4-methylumbelliferone, producing a fluorescent signal for sensitive fluorometric assays in lysosomal enzyme studies and biochemical assay development.
- Fluorogenic substrate for α-L-iduronidase assays.
- Enables sensitive fluorometric detection via 4-methylumbelliferone release.
- Suitable for enzyme kinetics and biochemical assay development.
- Available in small research quantities (μg-mg scale).
- Store protected from light at -20°C; in solvent, -80°C (6 months) or -20°C (1 month).